Limited Time Offer: Use code ORF50OFF at checkout for 50% Off. Shop Now

Off the Shelf Biologics

View Catalog

Recombinant Proteins & Growth Factors

ORF Biologics supplies ready-to-ship recombinant proteins for life science research, including recombinant growth factors and cytokines used every day in cell culture. Each protein is produced and tested in-house, with greater than 95% purity by SDS-PAGE, endotoxin below 1 EU/µg, and biological activity confirmed in a cell-based assay. Choose from sizes of 10 µg to 1 mg, or browse growth factors for cell culture by research area below.

Shop by Research Area

Not sure where to start? These are the cell culture growth factors researchers most often pair with each area of work.

Stem Cell & Organoid Culture

Stem cell growth factors for maintaining pluripotency, directing differentiation and building organoid models.

Activin A

FGF-2

Noggin

Wnt-3a

TGF-β1

Neuroscience

Proteins for neuronal survival, outgrowth and neural induction in culture.

BDNF

Noggin

FGF-2

Angiogenesis & Tissue Repair

Growth factors for endothelial cell culture, angiogenesis assays, wound healing and fibrosis models.

VEGF-165

FGF-2

PDGF-BB

TGF-β1

Bone & Immune Biology

Recombinant cytokines for osteoclast differentiation, bone remodeling and immune signaling studies.

RANKL

RANKL (His Tag)

TGF-β1

Noggin

Recombinant Proteins Built for Reproducible Research

Results are only as reliable as the research reagents behind them. Every ORF Biologics recombinant protein is tested at multiple stages of production so each lot performs like the last.

95% Purity — Identity and purity verified by SDS-PAGE.

<1 EU/µg Endotoxin — Endotoxin monitored on every product.

Verified Bioactivity — Activity confirmed in a cell-based assay suited to each protein.

Lot-to-Lot Consistency — Every batch held to the same specifications.

As a U.S.-based recombinant protein supplier in Tiffin, Iowa, ORF Biologics designs, expresses and purifies proteins using mammalian (CHO and HEK), E. coli, Bacillus subtilis and Pichia expression systems, giving life science reagents the folding and post-translational modifications each protein needs.

Compare Recombinant Growth Factors and Cytokines

All proteins are human sequence and available in 10 µg, 50 µg, 100 µg, 500 µg and 1000 µg sizes.

ProteinFamilyCommon research usesForm
Recombinant Human Activin ATGF-β superfamilyStem cell maintenance; endoderm and pancreatic differentiationLyophilized
Recombinant Human BDNFNeurotrophinNeuronal differentiation and outgrowth; neural stem cell maintenanceLyophilized
Recombinant Human FGF-2 (basic FGF)FGF familyiPSC and MSC expansion; angiogenesis; wound healingLyophilized
Recombinant Human NogginBMP antagonistNeural induction; organoid models; skeletal development studiesLyophilized
Recombinant Human PDGF-BBPDGF familyMesenchymal cell proliferation and migration; fibrosis modelingLyophilized
Recombinant Human RANKLTNF superfamilyOsteoclast differentiation; bone metabolism researchLyophilized
Recombinant Human RANKL, His TagTNF superfamilyBinding and interaction assays; osteoclast differentiationLiquid
Recombinant Human TGF-β1TGF-β superfamilyEMT and fibrosis models; Treg induction; stem cell differentiationLyophilized
Recombinant Human VEGF-165VEGF-A familyEndothelial cell proliferation; angiogenesis assaysLyophilized
Recombinant Human Wnt-3aWnt familyPluripotent stem cell maintenance; organoid developmentLyophilized

Recombinant Protein FAQs

What are off-the-shelf biologics?

Off-the-shelf biologics are catalog recombinant proteins, such as growth factors and cytokines, that are already manufactured, tested and ready to ship. They are an alternative to custom production when a standard, well-characterized protein fits your protocol.

How are ORF Biologics recombinant proteins tested?

Each protein is checked for identity and purity by SDS-PAGE (greater than 95%), endotoxin (below 1 EU/µg), and biological activity in a cell-based assay. The specific assay is listed on each product page. For example, FGF-2 activity is confirmed by Balb/c 3T3 cell proliferation and VEGF-165 by HUVEC proliferation.

What sizes are available?

Every catalog protein is offered in 10 µg, 50 µg, 100 µg, 500 µg and 1000 µg sizes. Bulk quantities and custom formulations are available on request.

How should I store and reconstitute growth factors?

Storage temperature and the recommended reconstitution buffer vary by protein and are listed in the Product Specifications table and data sheet on each product page. Avoid repeated freeze/thaw cycles.

Do you offer custom recombinant proteins?

Yes. If the protein, tag, species or scale you need isn’t in the catalog, our custom biologics team can design and produce it.

Need a protein that isn’t in the catalog?

ORF Biologics produces custom recombinant proteins, bulk quantities and custom formulations for labs with specialized requirements.

Explore Custom Biologics